Naturally Treats the Root Metabolic Cause of Diabetic Peripheral Neuropathy
Pain, Tingling and Sensation
Normalizes Glutathione Levels Reducing Oxidative Stress
Reduces High Homocysteine and Cellular Inflammation
Improves Vascular Function by Restoring Nitric Oxide
Improves Endothelial Function
Reduces Endoplasmic Reticulum Stress
Remedies the Negative Effect of Metformin on B12 Absorption and Folate Metabolization
Normalizes & Balances Serotonin, Dopamine, and Norepinephrine Production
Eliminates Negative Effects of MTHFR SNP Genotypes
In two large, well-designed clinical trials L-methylfolate, Methylcobalamin, and Pyridoxal-5 Phosphate demonstrated effectiveness and safety for the alleviation of symptoms of Peripheral Diabetic Neuropathy. Fonseca, The American Journal of Medicine, 2013 and McNamara, Journal of Diabetes Mellitus, 2016
In a large well designed clinical trial in patients with major depressive disorder and MTHFR polymorphism EnLyte reduced homocysteine 30% compared to placebo and remitted 42% of the active groups MDD in 8 weeks with side effects the same as placebo. Mech, The Journal of Clinical Psychiatry, 2016
Vitamin D is an independent risk factor for peripheral diabetic neuropathy. Shehab, Diabetic Med, 2012
Zinc and Magnesium are the two most common mineral deficiencies in diabetic neuropathic pain. Jack Kruge MD
Zinc supplementation alleviates diabetic peripheral neuropathy by inhibiting oxidative stress. Liu, Biol Trace Elem Res, 2014
Magnesium L-Threonate prevents and restores memory deficits associated with neuropathic pain by inhibition of TNF-a and has been shown to relieve chronic neuropathic pain. Wang, Pain Physician, 2013